Ethoxyquin: An Antioxidant Used in Animal Feed
نویسندگان
چکیده
Ethoxyquin (EQ, 6-ethoxy-1,2-dihydro-2,2,4-trimethylquinoline) is widely used in animal feed in order to protect it against lipid peroxidation. EQ cannot be used in any food for human consumption (except spices, e.g., chili), but it can pass from feed to farmed fish, poultry, and eggs, so human beings can be exposed to this antioxidant. The manufacturer Monsanto Company (USA) performed a series of tests on ethoxyquin which showed its safety. Nevertheless, some harmful effects in animals and people occupationally exposed to it were observed in 1980's which resulted in the new studies undertaken to reevaluate its toxicity. Here, we present the characteristics of the compound and results of the research, concerning, for example, products of its metabolism and oxidation or searching for new antioxidants on the EQ backbone.
منابع مشابه
Preparation of ethoxyquin salts and their genotoxic and antioxidant effects on human lymphocytes
Ethoxyquin phosphate (EQ-P) and ethoxyquin hydrochloride (EQ-HCl) were synthesized and studied for genotoxic and antioxidant activities with the use of comet assay and micronucleus test performed on human lymphocytes. The results were compared with the activities of the earlier studied ethoxyquin (EQ; 1,2-dihydro-6-ethoxy-2,2,4-trimethylquinoline), a strong antioxidant used mainly as a preserva...
متن کاملHigh-performance liquid chromatography coupled with chemiluminescence nitrogen detection for the study of ethoxyquin antioxidant and related organic bases.
The Chemiluminescent Nitrogen Detector (CLND) for use with high-performance liquid chromatography (HPLC) allows for the low-level detection of nitrogen-containing compounds with simple quantitation. The nitrogen selective detector's equimolar response (i.e., equal response for nitrogen independent of its chemical environment) allows for any nitrogen-containing compound to be quantitated as long...
متن کامل[Hypersensitivity to the antioxidant ethoxyquin].
Further to case reports published on occupational illnesses due to contact dermatitis caused by the antioxidant ethoxyquin,1,2 we report a patient with delayed hypersensitivity to this product who experienced a flare-up after patch testing. Ethoxyquin is used to prevent the oxidation of feed and essential oils, and in some countries to preserve the color of spices and fruit.3 The patient was a ...
متن کاملCarbohydrate fermentation and nitrogen metabolism of a finishing beef diet by ruminal microbes in continuous cultures as affected by ethoxyquin and(or) supplementation of monensin and tylosin.
Long-term feedlot studies have shown positive effects (i.e., improved ADG and reduced morbidity and mortality) of dietary supplementation with ethoxyquin (AGRADO). This may be due to improving the antioxidant capacity at the ruminal, postruminal, or postabsorption levels. This study was designed to investigate the role of ethoxyquin at the rumen level. A finishing diet (12.5% CP; DM basis) was ...
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عنوان ژورنال:
دوره 2013 شماره
صفحات -
تاریخ انتشار 2013